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Bruce C Trapnell Selected Research

Therapeutics

6/2024A toxicology study of Csf2ra complementation and pulmonary macrophage transplantation therapy of hereditary PAP in mice.
5/2024MRI and Blood-based Biomarkers Are Associated With Surgery in Children and Adults With Ileal Crohn's Disease.
10/2020Inhaled Molgramostim Therapy in Autoimmune Pulmonary Alveolar Proteinosis.
1/2019Long-Term Safety and Efficacy of Gene-Pulmonary Macrophage Transplantation Therapy of PAP in Csf2ra-/- Mice.
1/2018Clinical Significance of Interferon-γ Neutralizing Autoantibodies Against Disseminated Nontuberculous Mycobacterial Disease.
1/2018Personalised CFTR pharmacotherapeutic response testing and therapy of cystic fibrosis.
1/2017Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study.
1/2016Whole lung lavage therapy for pulmonary alveolar proteinosis: a global survey of current practices and procedures.
8/2013Serum VEGF-D a concentration as a biomarker of lymphangioleiomyomatosis severity and treatment response: a prospective analysis of the Multicenter International Lymphangioleiomyomatosis Efficacy of Sirolimus (MILES) trial.
6/2012Perspectives for improving the evaluation and access of therapies for rare lung diseases in Europe.
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Bruce C Trapnell Research Topics

Disease

36Pulmonary Alveolar Proteinosis
06/2024 - 01/2002
18Lung Diseases (Lung Disease)
12/2023 - 10/2008
10Respiratory Insufficiency (Respiratory Failure)
01/2022 - 03/2009
7Crohn Disease (Crohn's Disease)
05/2024 - 04/2009
7Cystic Fibrosis (Mucoviscidosis)
01/2020 - 12/2009
7Infections
01/2018 - 12/2002
5Lymphangioleiomyomatosis (Lymphangiomyomatosis)
01/2019 - 09/2010
4Inflammation (Inflammations)
06/2024 - 05/2011
4Disease Progression
11/2023 - 01/2019
4Autoimmune Diseases (Autoimmune Disease)
11/2014 - 03/2009
4Ileal Diseases
09/2013 - 05/2011
3Pulmonary Fibrosis (Fibrosing Alveolitis)
06/2024 - 10/2011
3Acquired Pulmonary Alveolar Proteinosis
12/2022 - 04/2008
3Interstitial Lung Diseases (Interstitial Lung Disease)
01/2022 - 10/2004
3Pneumonia (Pneumonitis)
06/2021 - 01/2018
3Emphysema
01/2020 - 09/2010
3Tuberous Sclerosis (Bourneville's Disease)
01/2019 - 09/2010
3Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2018 - 04/2009
3Sepsis (Septicemia)
01/2018 - 07/2002
3Ileitis
02/2012 - 04/2009
2Rare Diseases (Rare Disease)
01/2022 - 10/2020
2Chronic Obstructive Pulmonary Disease (COPD)
01/2022 - 04/2011
2COVID-19
06/2021 - 08/2020
2Hypoxia (Hypoxemia)
10/2020 - 04/2008
2Dyspnea (Shortness of Breath)
01/2016 - 11/2014
2Pediatric Crohn's disease
09/2013 - 02/2012
2Granuloma
06/2012 - 06/2005
2Fibrosis (Cirrhosis)
06/2012 - 10/2011
2Exocrine Pancreatic Insufficiency
09/2011 - 12/2009
1Bronchial Spasm
06/2024
1Asthma (Bronchial Asthma)
01/2022
1Giant Cell Arteritis (Horton Disease)
01/2022
1Chest Pain (Chest Pains)
10/2020
1Fever (Fevers)
08/2020
1Polycythemia (Erythrocytosis)
01/2020
1Macrophage Activation Syndrome
11/2019
1Ulcerative Colitis
01/2018
1Hemoptysis
10/2015
1Respiratory Sounds (Crackle)
10/2015
1Tachypnea
10/2015
1Pathologic Constriction (Stenosis)
09/2013
1Neoplasms (Cancer)
08/2013
1Neoplasm Metastasis (Metastasis)
08/2013
1Vascular Diseases (Vascular Disease)
08/2013
1Cysts
08/2013
1Cardiovascular Diseases (Cardiovascular Disease)
08/2013

Drug/Important Bio-Agent (IBA)

41Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
01/2024 - 01/2002
22Surface-Active Agents (Surfactants)IBA
06/2024 - 02/2004
21AutoantibodiesIBA
12/2022 - 02/2004
14Biomarkers (Surrogate Marker)IBA
05/2024 - 04/2008
6Granulocyte-Macrophage Colony-Stimulating Factor Receptors (GM-CSF Receptor)IBA
01/2022 - 11/2010
6Pulmonary Surfactants (Pulmonary Surfactant)IBA
01/2022 - 04/2008
5Proteins (Proteins, Gene)FDA Link
01/2022 - 05/2007
4AntibodiesIBA
06/2024 - 04/2011
4Acetaminophen (Paracetamol)FDA LinkGeneric
11/2023 - 03/2009
4Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA
01/2022 - 07/2010
4IndiumIBA
01/2022 - 06/2012
4lipoarabinomannan (LAM)IBA
01/2019 - 09/2010
3mavrilimumabIBA
01/2022 - 08/2020
3Sirolimus (Rapamycin)FDA Link
01/2019 - 04/2011
3Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
02/2012 - 04/2009
2EnzymesIBA
12/2022 - 09/2010
2Monoclonal AntibodiesIBA
06/2021 - 08/2020
2Interleukin-18 (Interleukin 18)IBA
11/2019 - 12/2002
2trans-sodium crocetinate (crocetin)IBA
01/2019 - 09/2010
2Anti-Bacterial Agents (Antibiotics)IBA
01/2018 - 01/2012
2CholesterolIBA
01/2017 - 06/2012
2LipidsIBA
01/2017 - 07/2010
2indium tin oxideIBA
01/2016 - 11/2014
2Vascular Endothelial Growth Factor DIBA
08/2013 - 09/2010
2Messenger RNA (mRNA)IBA
02/2012 - 07/2010
2CytokinesIBA
12/2011 - 08/2010
1Chemokine ReceptorsIBA
12/2023
1GasesIBA
11/2023
1ImmunosorbentsIBA
12/2022
1STAT5 Transcription FactorIBA
01/2022
1Prednisone (Sone)FDA LinkGeneric
01/2022
1C-Reactive ProteinIBA
06/2021
1molgramostimIBA
10/2020
1Matrix Metalloproteinases (MMPs)IBA
01/2020
1Interleukin-1 (Interleukin 1)IBA
01/2020
1SmokeIBA
01/2020
1Bronchodilator Agents (Bronchodilators)IBA
01/2019
1Interleukin-10 (Interleukin 10)IBA
01/2018
1InterferonsIBA
01/2018
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2018
1Phenobarbital (Luminal)FDA Link
09/2013
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
08/2013

Therapy/Procedure

16Therapeutics
06/2024 - 07/2002
3Enzyme Replacement Therapy
01/2020 - 12/2009
2Transplantation
06/2024 - 10/2014
2Artificial Respiration (Mechanical Ventilation)
08/2020 - 10/2015
2Drug Therapy (Chemotherapy)
01/2018 - 01/2017
2Cell- and Tissue-Based Therapy (Cell Therapy)
10/2014 - 08/2013
1Cell Transplantation
06/2024
1Palliative Care (Palliative Therapy)
11/2023
1Biological Therapy
11/2019
1Ligation
01/2018
1Punctures
01/2018
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
10/2014